Synbiotic Moisturiser

Issada Synbiotic Moisturiser with cream swatch, a microbiome-restoring and calming hydrator.
Issada Synbiotic Moisturiser bottle with box packaging, a microbiome-restoring and calming hydrator from the Clinical Formula range.
Smiling woman holding ISSADA Synbiotic Moisturiser with a green cream swatch on her cheek against a white background.
Issada Synbiotic Moisturiser surrounded by key ingredients including live probiotics, squalane, beta glucan, rosehip oil, and cucumber seed oil.
Issada Synbiotic Moisturiser with labeled key ingredients including live probiotics, squalane, beta glucan, rosehip oil, and cucumber seed oil.
Issada Synbiotic Moisturiser with icons showing it is vegan, cruelty free, gluten free, and paraben free.
Issada Synbiotic Moisturiser with benefits highlighting hydration, firmness, barrier repair, redness reduction, and balanced skin microbiome.
Issada Synbiotic Moisturiser bottle standing on a minimal background with product name and logo displayed.
Issada Synbiotic Moisturiser in white bottle packaging, a calming and hydrating formula that supports the skin’s microbiome.

Synbiotic Moisturiser

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Regular price$103.00
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You loved our Calming Probiotic Moisturiser, so meet its upgrade: ISSADA Synbiotic Moisturiser.

A barrier-restoring moisturiser that delivers prebiotics, over 1.5 million live probiotics and postbiotics to help restore a healthy skin microbiome within 30 minutes of application. It deeply hydrates, calms the look of redness and leaves stressed, sensitised skin feeling comfortable again.

Product Size: 50ml/1.69 fl. oz

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Synbiotic Moisturiser – Microbiome Restoring & Calming Hydrator

You loved our Calming Probiotic Moisturiser, so meet its upgrade – ISSADA Synbiotic Moisturiser.

Your skin barrier and your skin microbiome work as a team. The microbiome is the community of friendly bacteria living on your skin's surface. When it's in balance, your barrier holds moisture in and keeps irritants out. Over-cleansing, harsh actives, pollution, stress and in-clinic treatments can all upset that balance. Skin then feels dry and tight, and looks red and reactive.

"Synbiotic" means prebiotics, probiotics and postbiotics all working together, and ISSADA Synbiotic Moisturiser delivers all three in one probiotic moisturiser, including over 1.5 million live probiotics. It helps restore a healthy skin microbiome within 30 minutes of application, and rebuilds a stronger, more resilient skin barrier.

How a probiotic moisturiser works

  • Prebiotic – Inulin from chicory root. Feeds your skin's beneficial bacteria so they can thrive, and draws moisture into the skin.
  • Live probiotic – Bacillus subtilis. A skin-friendly bacterium known for producing polyglutamic acid, which helps skin hold water and reinforces the barrier. Its tough outer coat keeps it stable in the formula.
  • Postbiotic – Lactobacillus plantarum. Supports your skin's natural defences and its natural moisturising factor.
  • Cosmeceutical Synbiotic catalyst – Terminalia chebula. A long-lasting antioxidant that supports collagen. In an 8-week study of the ingredient with 52 people, skin texture, firmness, hydration, evenness and radiance all improved compared with a placebo.

Oat beta-glucan, squalane, rosehip oil and cucumber seed oil soothe, soften and help lock in moisture. It's light enough for combination skin and nourishing enough for dry skin.

A skin barrier moisturiser for sensitive, redness-prone skin

Ideal for: sensitive or reactive skin, skin prone to redness, dry or dehydrated skin, mature skin, and skin recovering after professional treatments.

The result: skin that feels calm, comfortable and hydrated, with a stronger barrier and a balanced microbiome. Over time it looks smoother, firmer and more radiant.

Key ingredients

  • Cosmeceutical Synbiotic (Terminalia chebula, Bacillus subtilis, Lactobacillus plantarum)
  • Inulin (prebiotic)
  • Oat Beta-Glucan
  • Squalane
  • Rosehip Oil
  • Cucumber Seed Oil

Want to know more? Read our guides to probiotics for skin health and repairing your skin barrier, or see our sensitive and barrier-impaired skin range.

VEGAN / CRUELTY-FREE / PARABEN FREE / GLUTEN FREE / PALM OIL FREE / NO SYNTHETIC FRAGRANCE / DERMATOLOGICALLY TESTED & APPROVED FOR SENSITIVE SKIN

Australian made in our own factory.

Product Size: 50ml/1.69 fl. oz

Product Features:

• Delivers prebiotics, over 1.5 million live probiotics and postbiotics in one moisturiser.
• Helps restore a healthy skin microbiome within 30 minutes of application.
• Feeds the skin's beneficial bacteria so they can thrive.
• Strengthens and helps restore the skin barrier.
• Deeply hydrates and helps reduce moisture loss.
• Supports the skin's own ceramides and natural moisturising factor.
• Calms the look of redness and soothes irritated skin.
• Antioxidant protection against pollution and daily environmental stress.
• Supports collagen for firmer, smoother-looking skin.
• Softens the look of fine lines and wrinkles.
• Dermatologically tested & approved for sensitive skin.

Product Benefits:

Leaves skin calm and comfortable, with a restored skin barrier, a balanced microbiome and lasting hydration, for smoother, firmer and more radiant-looking skin.

Aqua, Glycerine, Squalane, Simmondsia Chinensis (Jojoba) Seed Oil, Oryza Sativa (Rice) Bran Oil, Lecithin, Sodium Acrylates Copolymer, Rosa Canina (Rosehip) Seed Oil, Cetearyl Alcohol, Glyceryl Stearate Citrate, Polyglyceryl-3 Stearate, Inulin, Terminalia Chebula Extract, Bacillus Subtilis, Lactobacillus Plantarum, Beta Glucan (Oat), Phenoxyethanol, Ethylhexylglycerin, Cucumis Sativus (Cucumber) Seed Oil, Eucalyptus Globulus (Tasmanian Blue Gum) Leaf Oil, Lavandula Angustifolia (Lavender) Oil, Pelargonium Graveolens (Rose Geranium) Flower Oil, Titanium Dioxide, CI 77289, CI 77492

Use morning and night, after cleansing.
Apply your ISSADA serums first, allowing 30 seconds between each for your skin to absorb.
Warm 2–3 pumps between your hands and press gently onto the face and neck, using only a little around the eye contour area.
In the morning, always finish with sunscreen.

What does ISSADA Synbiotic Moisturiser do?

It's a daily probiotic moisturiser that delivers prebiotics, over 1.5 million live probiotics and postbiotics to help restore a healthy skin microbiome within 30 minutes of application. It deeply hydrates, strengthens the skin barrier and calms the look of redness.

What does synbiotic mean? Is it synbiotic or symbiotic?

It's "synbiotic", with an n. In skincare it means biotics working together: a prebiotic (inulin) feeds your skin's friendly bacteria, a live probiotic (Bacillus subtilis) adds beneficial bacteria, and a postbiotic (Lactobacillus plantarum) supports your skin's natural defences. "Symbiotic" is a different word, although it's a nice way to think about your skin and its friendly bacteria, because each helps the other.

Does it contain live probiotics?

Yes, over 1.5 million live probiotics. The probiotic is Bacillus subtilis, a skin-friendly bacterium with a tough protective outer coat, so it stays stable in the cream. To learn more, read our guide to probiotics for skin health.

Is it a good moisturiser for a damaged skin barrier?

Yes, that's what it was made for. Over-cleansing, harsh actives, pollution, stress and in-clinic treatments can all leave the skin barrier feeling dry, tight and reactive. ISSADA Synbiotic Moisturiser deeply hydrates, helps reduce moisture loss and helps restore a stronger barrier. For more tips, read our skin barrier repair guide.

Is it suitable for sensitive skin and redness?

Yes. It has been dermatologically tested and approved for sensitive skin, and it calms the look of redness. It contains no synthetic fragrance. It does contain small amounts of natural essential oils (lavender, rose geranium and Tasmanian blue gum), so if you know you react to any of these, patch test first on the inner arm.

What happened to Calming Probiotic Moisturiser?

ISSADA Synbiotic Moisturiser is its upgrade. If you loved our Calming Probiotic Moisturiser, this is the one to choose now. It brings prebiotics, live probiotics and postbiotics together in one moisturiser.

Serum or moisturiser first? Where does it go in my routine?

Serum first, then moisturiser. Morning and night, cleanse with our Daily Gentle Cleansing Gel, then apply your serums, such as our Pure Hyaluronic Serum or Niacinamide + B5 Complex, allowing 30 seconds between each. Finish with ISSADA Synbiotic Moisturiser. In the morning, always finish with sunscreen.

Which skin types is it for?

It's light enough for combination skin and nourishing enough for dry skin. It's especially good for sensitive, reactive or redness-prone skin, dehydrated skin, mature and menopausal skin, and skin recovering after professional treatments.

Can I wear it under makeup?

Yes. Give it a minute or two to sink in first. If redness is your main concern, follow with our Calm Balm Mineral Foundation Primer, whose green tint helps neutralise the look of redness before foundation.

Is it vegan, palm oil free and Australian made?

Yes. It's Australian made in our own factory, and it's vegan, cruelty free, paraben free, gluten free and palm oil free.

Is beta glucan gluten? Is this moisturiser gluten free?

No, beta glucan isn't gluten, and yes, ISSADA Synbiotic Moisturiser is gluten free. The names sound alike, but they're completely different things. Gluten is a protein found in wheat, barley and rye. Beta glucan is a natural sugar (a type of fibre) that we use for its hydrating, skin-soothing benefits.

Overall rating: 5.0 / 5 from 16 reviews.

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Reviews

One of my new favourites

"Having more mature skin and till having the occasional break out during menopause, this product has been a revelation. It has cleared the redness and reduced the break outs. I have only had it for a few weeks and am really pleased with the results so far!"

— Rebecca (5/5)

Amazing product!!

"My skin has never felt better, and the redness has reduced considerably after only a couple of weeks of use. This will be my go-to moisturiser forever!!"

— Theresa T. (5/5)

Solved my skin issues!

"This moisturiser got my skin back to normal after a year of breakouts that not even my derm could work out what it was from. It was amazing how quickly it worked in just a few days. While it does contain quite a few natural oils, it did not clog my pores or make me feel greasy. Just love this cream"

— Anna (5/5)

Highly recommend

"Absolutely love this moisturiser. It is light and non-greasy and my skin has never looked better. It looks like I’ve put a primer on my skin! It fills in my pores, reduces redness and is mattifying, making my skin look fantastic. I’m so happy. Highly recommend for people struggling with their pores and redness."

— Belinda (5/5)

Love all ISSADA products. Skin

"Love all ISSADA products. Skin feels & looks fabulous. Recommend all skincare range. Makeup range is beautiful also. Great prices."

— Wendy P. (5/5)

Soothing and light

"This product is so lovely. My skin has been angry lately (acne and rosacea) and this beautiful product is so soothing. I could tell the moment I first applied it, that it was doing some good. Early days yet but I think I’m in love. It smells delightful too."

— Lee T. (5/5)

Velvety Smooth

"Love the texture and smoothness of this moisturiser. Well worth it. Love Essada products."

— Joanne M. (5/5)

Brilliant

"I have survived winter because of this!! It smells lovely and feels nice. I have super sensitive skin and had no burning at all and has made my skin feel comfortable all the time! I generally dont wear moisturiser because it makes me break out! Nothing at all with this one!! Will def be making this my everyday moisturizer"

— Andrea D. (5/5)

Go-to moisturiser

"Introduced to Issada over 10yrs ago, still my go-to moisturiser for problematic skin"

— Janna A. (5/5)

Another plus for issada

"Pleasant smelling, feels lovely on my skin. Love how my skin feels with this on!"

— Andrea L. (5/5)

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