A healthy, resilient complexion begins with balance. Beneath the surface, the skin hosts a diverse ecosystem of bacteria, fungi, and other microorganisms. Known as the skin microbiome, this microbial community plays a key role in how the skin looks, feels, and responds to stress.
Research into the skin microbiome continues to grow, and so does our understanding of how to support it. One of the most promising approaches to maintaining balance and integrity in the skin barrier is through the use of probiotics. Whether applied topically or taken orally, probiotics help manage inflammation, strengthen the skin barrier, and promote overall skin clarity.
What Is the Skin Microbiome?
The skin microbiome is a living layer made up of trillions of microorganisms that coexist on the surface of the skin. These microbes help maintain skin health by regulating pH, preventing the overgrowth of harmful bacteria, supporting immune function, and preserving hydration.
When the microbiome is balanced, the skin is better equipped to defend against environmental stressors, allergens, and pathogens. However, harsh skincare products, stress, antibiotics, and even weather changes, which are common across cities like Melbourne, can disturb this balance, leading to skin sensitivity, dryness, or breakouts.
Understanding this invisible ecosystem is essential for both consumers and skincare professionals. A well-functioning microbiome works synergistically with the skin's immune system to calm inflammation and preserve the skin’s ability to retain moisture and heal itself naturally.
The Role of Probiotics in Skin Health

Probiotics are live, beneficial microorganisms that promote microbial balance. While most people associate them with gut health, they also provide advantages when used in skincare or consumed through diet.
Features of Probiotics:
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Live strains of beneficial bacteria, commonly Lactobacillus and Bifidobacterium
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Found in fermented foods, supplements, and advanced skincare formulations
Key Benefits:
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Helps restore microbial balance on the skin
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Supports the skin barrier against moisture loss
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Aids in calming inflammation and visible redness
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Encourages smoother, more resilient skin
By introducing beneficial bacteria, probiotics assist in maintaining harmony between good and potentially harmful microbes. This microbial equilibrium plays an essential role in managing conditions such as acne, eczema, and rosacea.
The Gut–Skin Connection: Why It Matters
The gut and skin are closely connected through what’s known as the gut–skin axis. Digestive imbalances, such as those caused by a poor diet, food intolerances, or high-stress levels, can trigger inflammation that shows up on the skin.
Common signs of gut imbalance that may affect skin include:
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Persistent breakouts
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Redness or rosacea-like flare-ups
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Dry or itchy patches
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Sensitivity to skincare products
Supporting gut health with probiotics can help improve digestion and reduce systemic inflammation, both of which benefit skin clarity and comfort. This internal approach complements topical skincare and supports results from within.
Topical vs Oral Probiotics: A Dual Approach
Skincare containing live probiotic strains supports the skin microbiome directly at the surface. A standout option is theISSADA Synbiotic Moisturiser, which contains over a billion live probiotics per gram (plus pre‑ and post‑biotics) and helps restore microbial balance within 30 minutes of application.
Topical Probiotics:
Applied directly to the skin, these products help reinforce the microbiome. They are commonly found in serums, moisturisers, and cleansers.
Topical Benefits:
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Helps soothe irritated or inflamed skin
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Promotes hydration by strengthening the moisture barrier
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Supports post-treatment skin recovery in clinic environments
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Enhances resilience to environmental stressors
Oral Probiotics:
Found in capsules, powders, or fermented foods, oral probiotics work internally to support gut balance.
Oral Benefits:
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Modulates immune response to external stressors
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Reduces gut-driven inflammation that can affect the skin
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Improves nutrient absorption for overall skin nourishment
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Supports long-term skin clarity and balance
Conditions That May Improve With Probiotic Use
Acne
Probiotic strains like Lactobacillus reuteri can help regulate sebum production, balance P. acnes bacteria, and reduce inflammation, supporting clearer skin.
Eczema
Certain strains, including Lactobacillus rhamnosus and Bifidobacterium breve, are known to strengthen the skin barrier and reduce eczema flare-ups.
Rosacea
By calming overactive immune responses and reducing redness, probiotics may assist in minimising rosacea symptoms over time.
Skin Sensitivity
Sensitive skin often results from a compromised barrier. Probiotics help reinforce the barrier function and reduce inflammatory responses.
How to Incorporate Probiotics Into a Skincare Routine
For clients or clinics looking to support skin resilience through microbiome care, a combined internal and external approach works best.
Topical Skincare:
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Choose skincare products that contain live probiotic strains or prebiotics (which feed good bacteria)
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Look for formulations free from harsh surfactants, alcohol, or artificial fragrance
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Apply consistently as part of a morning or evening routine
Nutrition and Supplementation:
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Include fermented foods such as kefir, sauerkraut, kimchi, miso, and kombucha in daily meals
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Choose high-quality probiotic supplements that include clinically studied strains
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Pair with a balanced, whole-food diet rich in fibre, which acts as a prebiotic
Considerations and Safety
Probiotics are generally well-tolerated. However, those with very sensitive skin or compromised immune systems should introduce probiotic skincare gradually or consult a healthcare provider before starting supplements.
Choosing products with transparent ingredient listings and clinically tested strains helps ensure both safety and effectiveness.
Clinical Implications for Skincare Professionals
For clinic owners and dermal therapists, probiotic skincare offers a strategic opportunity to expand treatment protocols. Post-treatment care for IPL, peels, or microneedling can benefit significantly from topical probiotics to reduce inflammation, support barrier repair, and enhance visible recovery.
Incorporating probiotic-rich skincare lines in retail offerings also allows for continuity of care at home, reinforcing in-clinic results.
Key Takeaways
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The skin microbiome plays a central role in hydration, immune defence, and inflammation control
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Probiotics help maintain microbial balance and support a resilient skin barrier
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Both topical and oral probiotics are beneficial and can be used together
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Conditions like acne, eczema, and rosacea may respond positively to probiotic use
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Consistency is key, results typically appear within 4–6 weeks of ongoing use
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Professional clinics can enhance post-treatment outcomes using probiotic skincare
FAQs
Can probiotics improve acne-prone skin?
Yes, probiotics can help manage acne by balancing skin bacteria and reducing inflammation.
Are topical or oral probiotics more effective?
Both offer benefits. Oral probiotics address gut-related triggers while topical probiotics support the skin surface directly.
How long before I see results from using probiotics?
Results may appear within 4–6 weeks of consistent topical application or supplementation.
Is probiotic skincare suitable for sensitive skin?
Yes, but start with patch testing. Choose formulations without added fragrance or alcohol.
Can I combine probiotic skincare with professional treatments?
Yes, probiotic skincare may support post-treatment recovery and barrier repair after in-clinic procedures like IPL or facials.
Who should use ISSADA Synbiotic Moistuiser?
Anyone with "sensitive skin" or who suffers from acne, rosacia and dry or irritated skin . Use after microneedling, laser resurfacing, RF and Fractional RF treatments as well as Evo Plasma, HIFU and more.
How Often Should I use ISSADA Synbiotic Mousturiser?
ISSADA Synbiotic Mousturiser can be used morning and evening after your ISSADA cleanser and your favourite ISSADA serum - Niacinamide + B5 is a particularly good choice for rosacea, and irritated or inflamed skin.
I have acne - should I use the Synbiotic or Acne Prone moisturiser?
While both are good for acne we recommend the Acne-Prone moisturiser for Cystic acne and oily skin. The actives in this moisturiser will help to reduce sebum (oil) flow and clean out blocked pores.
Dry skin sufferers with acne (or those with acne-rosacea) will benefit more from the calming properties of our Synbiotc Moisturiser.
Explore ISSADA's microbiome-supporting formulas to help maintain clear, balanced, and healthy-looking skin from within and on the surface.
Need more help? Ask our cusomer service team who will be more than happy to help! Please Contact us here.
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