Drop element here

To reveal your most beautiful skin, did you know winter is the best time to introduce your skin to its best friend to obtain younger, smoother, healthier looking skin – and the secret is Retinol!

At ISSADA Cosmeceuticals, we believe Retinol should be introduced to your regime as soon as possible, and we have two variations of strengths to enable you to introduce Retinol easily and effectively. ISSADA Clinical Formula 0.5% Retinol + HA and ISSADA Clinical Formula 1% + HA. Both formulations also contain a therapeutic dose of Hyaluronic Acid to keep your skin super hydrated, whilst Retinol works to perfect your skin.

Retinol, a form of vitamin A, is a potent ingredient that offers numerous beneficial effects on the skin. It has been extensively studied and is widely used to target skin concerns due to its ability to promote healthier, more youthful-looking skin. Here are some of the main beneficial effects of Retinol on the skin:

0.5% Retinol + HA

If you haven’t used Retinol before, we recommend starting with our lower concentration ISSADA Clinical Formula 0.5% Retinol + HA Serum and gradually increasing usage to allow the skin to adapt. When your skin is ready you can graduate to the full-strength ISSADA Clinical Formula 1% Retinol +HA Serum.


1% Retinol + HA

For experienced Retinol users, go directly to ISSADA Clinical Formula 1% Retinol + HA Serum, or after your skin adjusts to our lower strength Retinol, to obtain the most advanced results.


8 Beneficial Effects of Retinol on the skin

Stimulates Collagen Production

Retinol helps to boost collagen production in the skin. Collagen is a protein responsible for maintaining skin elasticity and firmness. As we age, collagen production decreases, leading to wrinkles and sagging. By stimulating collagen synthesis, Retinol can improve skin texture and reduce the appearance of fine lines and wrinkles.

Promotes Cell Turnover

Retinol encourages the shedding of dead skin cells and accelerates the turnover of new skin cells. This process can help to unclog pores, prevent the formation of blackheads and whiteheads, and improve overall skin clarity.

Evens Skin Tone

Retinol can fade hyperpigmentation, dark spots, and age spots caused by sun damage or hormonal changes. It helps to inhibit the overproduction of melanin, the pigment responsible for skin colouration, resulting in a more even skin tone.

Reduces Acne

Retinol effectively treats acne and prevents new breakouts. It helps regulate sebum production, reduces inflammation, and unclogs pores, leading to clearer skin over time.

Improves Texture

Regular use of Retinol can lead to smoother and softer skin, as it helps to refine the skin's surface and promotes a more even texture.

Enhances Skin Hydration

Although Retinol needs to be slowly introduced, with continued use, it can improve the skin's ability to retain moisture, leading to better hydration.

Minimises Pore Size

Retinol can help reduce the appearance of enlarged pores by unclogging them and encouraging cell turnover, improving the skin's overall appearance.

Antioxidant Properties

Retinol acts as an antioxidant, protecting the skin from oxidative stress caused by free radicals. Retinol can help prevent premature aging and damage caused by environmental factors.

It's important to note that while Retinol provides significant benefits, this potent active ingredient needs to be introduced slowly so your skin adapts readily to its full benefits. If you haven’t used Retinol before, we recommend starting with our lower concentration ISSADA Clinical Formula 0.5% Retinol + HA Serum and gradually increasing usage to allow the skin to adapt. You can graduate to ISSADA Clinical Formula 1% Retinol + HA Serum as your skin adjusts to obtain the most effective results.It’s always a good idea to introduce Retinol slowly for first time users by applying every third day in the first two weeks, then increasing application to every second day for the next two weeks, and gradually to daily use or as tolerated by your skin.

Replenishing Daily Moisturiser

Retinol can increase the skin's sensitivity to the sun, so it's crucial to use it at night and wear ISSADA Clinical Formula Sheer Defence SPF50+ sunscreen during the day to protect the skin from harmful UV rays.


Regularly using Retinol will leave your skin looking younger, healthier, smoother and refined in texture, and clearer of any breakout with less visible pores.

ISSADA Clinical Formula Retinol + HA serums in two strengths are now available at

Follow us to know more

We are here to answer all of your queries

Follow us on social media